Tara Strong as Harlen Quinzel/Harley Quinn, Barbara-Ann "Barbi" Minerva/Cheetah, Ursa.
Sendhil Ramamurthy & Jason C Miller as Ra's Al Ghul.Cristina Milizia as Pamela Lillian Isley/Poison Ivy.Dee Bradley Baker as Ace the Bat-Hound, Krypto.Keith Ferguson as Bruce Wayne/Batman, Robin, Alfred Pennyworth, Shane O'Shaughnessy, Jeremiah Danvers, Francis Zeul.Griffin Puatu as Mortimer Drake/The Cavalier.Keith Ferguson as Thaal Sinclair/Sinestro.Kevin Michael Richardson as Dexter/Dex-Starr.Fred Tatasciore as Commissioner Gordon, Mr.Jason Spisak as Hal Jordan/Green Lantern.Eddie Perino as Oliver Queen/Green Arrow.Jessica McKenna as Garth Bernstein/Aqualad.Phil LaMarr as Barry Allen/The Flash, Mr.Kari Wahlgren as Carol Ferris/Star Sapphire.Myrna Velasco as Jessica Cruz/Green Lantern.Nicole Sullivan as Kara Danvers/Supergirl.Grey Griffin as Diana Prince/Wonder Woman.
The series follows the adventures of teenage versions of Wonder Woman, Supergirl, Bumblebee, Batgirl, Zatanna, and Green Lantern, who are students of Metropolis High School. The second season premiered in June 6, 2021. The new series debuted with a theatrical short, #TheLateBatsby, in 2018, and was continued with a Web Series called DC Super Hero Girls: Super Shorts in early 2019, which serves as a prelude to the TV series which premiered on Cartoon Network on March 8, 2019. 72 DC Super Hero Girls is an animated action-adventure series developed by Lauren Faust based on the original web series with the same name.